Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.18.07 | Pituitary–Basic and IGF-1 | ECE2015

The hypothyroidism alters circadian clock expression in anterior pituitary gland

Bargi-Souza Paula , Peliciari-Garcia Rodrigo A , Previde Rafael Maso , Nunes Maria Tereza

The anterior pituitary gland occupies a central position in the hypothalamus–pituitary glands axes and secretes hormones involved in reproduction, growth, and metabolism. The plasma concentrations of pituitary hormones present fluctuations during the 24 h and are markedly altered during the hypothyroidism. The presence of an intra-pituitary circadian oscillator might be related to these oscillations; however, the molecular mechanism and the consequences of the hypothyroid...